Garrus: If this ends with the both of us dying in a giant explosion killing a Reaper, just remember. I took the kill shot.
Legion: Human history is a litany of blood shed over different ideals of rulership and afterlife.
Shepard: The bartender over there?
Liara: The matriarch hired by the asari gouvernment to track my movements?
Shepard: She’s your father.
Eve: I should consider him an enemy. Yet I think seeing my sisters and I changed something in him.
Mordin: Asari-vorcha offspring have an allergy to dairy, and… da-di-di-dee-di-doo-doo-doo-
Shepard: Well it wasn’t his ear.
[Shepard sends a probe to uranus]
EDI: Really, Commander?
[launches another probe]
EDI: [sighs] Probing Uranus…
Legion: Does this unit have a soul?
Tali: Yes.
Traynor: What’s the difference between Commander Shepard and a krogan?
Shepard: I don’t know.
Traynor: One is a rampaging juggernaut of head-butting destruction…
Shepard: And the other doesn’t have a wisecracking assistant to keep in line.
Traynor: Oh that one is even funnier than the number of testicles punchline.
Garrus: You realize this plan has me walking into hell too… ha just like old times.
Garrus: I’m Garrus Vakarian and this is now my favorite spot on the Citadel!
Jack: Now take your balls out of your purse and kick some ass.
Tali: Don’t say “Ah” to me, you sound like a vorcha.
Javik: Your “Liara” asari asks many questions. You would think she’d never seen a prothean before.
Javik: This has been… amusing.
Shepard: Oh?
Javik: To discover the most primitive races of my time now rule the galaxy. The asari, the humans, the turians…
Liara: There’s also the salarians.
Javik: The lizard people evolved?
Liara: I believe they are amphibian.
Javik: They used to eat flies.
Liara: Joker, really? I have work to do.
Joker: Aw, come on it’s just one simple question.
Liara: Then look it up on the extranet.
Joker: You can’t believe everything you find there, it’s more reliable to ask a friendly asari.
Liara: I’m not telling you if my “hair tentacles” move!
Joker: Fine. Deny me the answer I’ve been seeking for years. With this war on, we could die at any second, you know.
Shepard: You know he’s going to keep bothering you till you tell him.
Liara: [sigh] They’re semi flexible cartilage-based scalp crests that grow into shape. And they don’t “flop around”.
Joker: Yes! Thanks Liara, I gotta tell Vega I was right.
Liara: Well, at least he’s making friends.
Tali: I heard about your talk with Liara. You act so angry, but you really care about us.
Javik: I need you functional to destroy the Reapers.
Tali: You care about Liara. You like her.
Javik: You are intoxicated. A foolish risk given quarian symbiotic physiology.
Tali: And you like me, too!
Javik: This conversation is over.